Self-repair (work in progress)
Laboratory. 2017-2018
n number of participants

Concept Contributions Contact


Contributions

SynORI - a framework for multi-plasmid systems
Mindaugas Gapševičius, Gabrielius Jakutis, Miglė Kalvaitytė, Lina
Rukevičiūtė, Emilija Vasiliūnaitė

The series of drawings introduce the Vilnius-Lithuania iGEM 2017 team's 
process of developing a SynORI - synthetic origin of replication. Under 
the same name the team has created a framework which, for the first time 
in science history, enables the alteration of plasmid copy number and 
standardized regulation of multi-plasmid systems. SynORI incorporates a 
subsystem for reducing the amount of antibiotics needed to maintain 
multiple plasmids in one cell, and will enable the creation of more 
complex metabolic pathways, smart assembly of protein complexes and a 
more precise information processing in synthetic biology.